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Developing a cosmetic, dermocosmetic or healthcare product requires both safety assessment and efficacy substantiation.
BioToSkin supports manufacturers throughout this process by combining internationally recognized OECD in vitro methods with advanced human skin models. Our expertise in reconstructed tissues, primary human cells and fresh human skin explants enables the generation of robust scientific data supporting regulatory compliance, product safety and product claims.
By integrating safety and efficacy testing within the same scientific framework, BioToSkin helps clients accelerate product development while strengthening both scientific and marketing value.
BioToSkin offers a range of OECD guideline-compliant methods based on validated human-relevant in vitro models, supporting product safety assessment while reducing animal testing.
Assessment of skin corrosion potential using reconstructed human epidermis models.
While OECD methods provide essential information regarding product safety, they do not explain how a product interacts with the skin or which biological pathways are affected.
BioToSkin complements regulatory testing with mechanistic studies performed on primary human cells and fresh human skin explants. This integrated approach allows manufacturers to assess both safety and biological activity while generating data that support product positioning, claim substantiation and marketing differentiation.
Fresh human skin explants preserve the native architecture of the skin and provide highly relevant tissue-level information. Through collaborations with surgical and aesthetic medicine centers, BioToSkin also has access to clinically relevant procedures and technologies, allowing the evaluation of topical products, injectables, microneedling procedures, lasers and energy-based treatments under controlled ex vivo conditions.
Examples of efficacy endpoints include:
This unique combination of regulatory testing, human skin biology and mechanistic research enables BioToSkin to transform scientific evidence into meaningful and differentiating product claims.
Why BioToSkin for Safety Testing ?
