Induced psoriasis on human skin explants: why the strongest stimulation gave us the weakest signal
16 July 2026
We tested three IL-17/IL-22 doses on human skin explants before running a single efficacy study.
The most aggressive cocktail produced the lowest inflammatory readout of the three. That result shaped how we build every disease model we run — and it is the reason a modest 39% induction window can still separate three topical formulations
